A molecular taxonomy for systemic autoimmune rheumatic diseases (SARDs): learning lessons from oncology?
نویسندگان
چکیده
منابع مشابه
A comparison of health-related quality of life (HRQoL) across four systemic autoimmune rheumatic diseases (SARDs)
OBJECTIVES To compare physical and mental health-related quality of life (HRQoL) across four systemic autoimmune rheumatic diseases (SARD). METHODS Incident subjects enrolled in four SARD cohorts, namely systemic lupus erythematosus (SLE), systemic sclerosis (SSc), rheumatoid arthritis (RA) and idiopathic inflammatory myopathies (IIM) were studied. The outcomes of interest were baseline Short...
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Autoimmune diseases encompass a wide range of organ-specific and systemic disorders with a complex etiology. An intricate interplay of genetic, environmental, as well as immunological factors leads to the development of these debilitating diseases. In the absence of infections, regulatory processes inhibit immune responses towards antigen. Moreover , the immune system has multiple levels of neg...
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Systemic autoimmune and rheumatic diseases (SAIRDs) are thought to develop due to the failure of autoimmune regulation and tolerance. Current therapies, such as biologics, have improved the clinical results of SAIRDs; however, they are not curative treatments. Recently, new discoveries have been made in immune tolerance and inflammation, such as tolerogenic dendritic cells, regulatory T and B c...
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The aim of this study was to determine whether inflammation is related to cancer development, and whether the incidence of cancer is increased and occurs in a site-specific manner in patients with systemic autoimmune rheumatic diseases (SARDs).This study included a nationwide dynamic cohort of patients with various newly diagnosed SARDs from 1997 to 2010 with follow-up until 2012.This study inc...
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1 Center for Autoimmune Diseases Research (CREA), Universidad del Rosario, Carrera 24 No. 63C-69, 111221 Bogota, Colombia 2 ZabludowitczCenter forAutoimmuneDiseases, ShebaMedical Center, Tel-Hashomer, Sackler Faculty ofMedicine, Tel AvivUniversity, 52621 Tel-Hashomer, Israel 3 Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin Charitéplatz 1, 10117 Berlin, Germany 4...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2020
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/keaa097